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Some joints may be primed for rheumatoid arthritis before birth
Science News

Some joints may be primed for rheumatoid arthritis before birth

Scientists have found evidence that vulnerability to rheumatoid arthritis may begin before birth. Finger joints commonly affected by the disease develop with different tissue structures and larger populations of specialized fibroblasts than joints that are usually spared. Those cells also respond differently to inflammation, suggesting that the architecture of each joint may help determine where arthritis eventually takes hold.

📅 2026-09-05 22:19:53    •    ScienceDaily
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Breaking through AlphaFold's limits to predict how proteins change shape
Science News

Breaking through AlphaFold's limits to predict how proteins change shape

Conformational changes in proteins are vital to their function yet remain challenging for state-of-the-art artificial intelligence, such as AlphaFold3, to predict. Researchers at the Institute for Molecular Science (IMS), and the Graduate University for Advanced Studies, SOKENDAI introduced a repulsive force between predicted structures, allowing AlphaFold3 to sample the multiple conformational states that its default settings rarely capture.

📅 2026-09-05 21:00:05    •    Phys.org
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Compound in blueberries may help muscle cells burn excess fat
Science News

Compound in blueberries may help muscle cells burn excess fat

Scientists in Japan have identified a natural compound found in blueberries, grapes, and other berries that may help muscle cells burn excess fat instead of storing it. The compound, pterostilbene, reduced abnormal fat buildup in cultured mouse muscle cells by boosting fat breakdown and helping stabilize a key protein involved in fatty acid metabolism.

📅 2026-09-05 19:30:40    •    ScienceDaily
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